A DELETERIOUS NAV1.1 MUTATION SELECTIVELY IMPAIRS TELENCEPHALIC INHIBITORY NEURONS DERIVED FROM DRAVET SYNDROME PATIENTS

A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients

Dravet Syndrome is an intractable form of childhood epilepsy associated with deleterious mutations in SCN1A, the gene encoding neuronal sodium channel Nav1.1.Earlier studies using human induced pluripotent stem cells (iPSCs) have produced mixed results regarding the importance of Nav1.1 in human inhibitory versus excitatory neurons.We studied a Nav

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Aggregate size distributions in hydrophobic flocculation

The evolution of aggregate (floc) size distributions resulting from hydrophobic flocculation has been investigated using a laser light scattering technique.By measuring floc size distributions it is possible to distinguish clearly among floc formation, growth and breakage.Hydrophobic flocculation of hematite suspensions with sodium oleate under a v

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E-books didáticos nos ambientes de aprendizagem em rede

Apresenta um estudo sobre a relação entre os e-books e o ambiente virtual de aprendizagem (AVA) suportado por dispositivos eletrônicos conectados à Internet.O objetivo é evidenciar as possibilidades e as vantagens do uso Ammonia Removers de e-books.Trata-se do resultado decorrente de uma pesquisa exploratória e estudos bibliográficos, caract

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E-books didáticos nos ambientes de aprendizagem em rede

Apresenta um estudo sobre a relação entre os e-books e o ambiente virtual de aprendizagem (AVA) suportado por dispositivos eletrônicos conectados à Internet.O objetivo é evidenciar as possibilidades e as vantagens do uso Ammonia Removers de e-books.Trata-se do resultado decorrente de uma pesquisa exploratória e estudos bibliográficos, caract

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Augmented and challenging datasets with multi-step reasoning and multi-span questions for Chinese judicial reading comprehension

The existing judicial reading comprehension ORGANIC SHEA BUTTER datasets are relatively simple, and the answers to the questions can be obtained through single-step reasoning.However, the content of legal documents in actual scenarios is complex, making it problematic to infer correct results merely by single-step reasoning.To solve this type of is

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